Signup date: 14 Jan 2013 at 9:20am
Last login: 21 Mar 2018 at 10:49am
Post count: 125
Title : AMPA glutamate receptor subunits are differentially distributed in rat brain
Authors : Martin LJ, Blackstone CD, Levey AI, Huganir RL, Price DL.
Publication Date : 1993
Direct Link : "www.sciencedirect.com/science/article/pii/030645229390199P"
Summary :
To demonstrate the regional, cellular and subcellular distributions of non-N-methyl-d-aspartate glutamate receptors in rat brain, we generated antipeptide antibodies that recognize the C-terminal domains of individual subunits of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-preferring glutamate receptors (i.e. GluR1, GluR4, and a region highly conserved in GluR2, GluR3 and GluR4c). On immunoblots, antibodies detect distinct proteins with mol. wts ranging from 102,000 to 108,000 in homogenates of rat brain.
Immunocytochemistry shows that glutamate receptor subunits are distributed abundantly and differentially within neuronal cell bodies and processes in cerebral cortex, basal ganglia, limbic system, thalamus, cerebellum and brainstem. The precise patterns and cellular localizations of glutamate receptor subunit immunoreactivities are unique for each antibody. In neocortex and hippocampus, pyramidal neurons express GluR1 and GluR2/3/4c immunoreactivities; many non-pyramidal, calcium-binding, protein-enriched neurons in cerebral cortex are selectively immunoreactive for GluR1. In striatum, the cellular localizations of GluR1, GluR2/3/4c and GluR4 immunoreactivities are different; in this region, GluR1 co-localizes with many cholinergic neurons but is only present in a minor proportion of nicotinamide adenine dinucleotide phosphate diaphorase-positive striatal neurons. GluR1 co-localizes with most dopaminergic neurons within the substantia nigra. In several brain regions, astrocytes show GluR4 immunoreactivity. Within the cerebellar cortex, cell bodies and processes of Bergmann glia express intense GluR4 and GluR1 immunoreactivities; perikarya and dendrites of Purkinje cells show GluR2/3/4c immunoreactivity but no evidence of GluR1 or GluR4. Ultrastructurally, GluR subunit immunoreactivities are localized within cell bodies, dendrites and dendritic spines of specific subsets of neurons and, in the case of GluR1 and GluR4, in some populations of astrocytes.
This investigation demonstrates that individual AMPA-preferring glutamate receptor subunits are distributed differentially in...
The former one :
http://www.sendspace.com/file/z5yqdq
To remove from server :
http://www.sendspace.com/delete/z5yqdq/37782e117585b3250909ead4c77007c9
Here it's :
http://www.sendspace.com/file/xqmwoe
To delete after downloading :
http://www.sendspace.com/delete/xqmwoe/e5d687c67c95cc153ccc06c14a6cf5a6
.
I'm not sure if it suits for your needs but there is "www.labarchives.com/".
For note-taking, "evernote" is almost perfect.
To store your files, "dropbox, box, google drive etc" may help.
My advice for writing and publishing is "Citavi" that has a free version which is enough for most purposes.
I'm sorry for being so late. Just noticed your post. You should send an e-mail to ask at the same time as you post to forum.
Article has been sent to your e-mail and also uploaded to :
www.sendspace.com/file/7dg12g
For removal from server :
www.sendspace.com/delete/7dg12g/c9a6d4a8673a8a1700f2878de8de3a53
"Clay-Mediated meso-Tetraarylporphyrin Synthesis" titled article is in link :
www.sendspace.com/file/p577g5
For removal from server following to download :
www.sendspace.com/delete/p577g5/361abcb8918a6e599908d9ddd256d7e7
I dont have access to next one. Sorry...
Here is the artcile : "www.sendspace.com/file/z2xm3k"
... and for removal from server : "www.sendspace.com/delete/z2xm3k/5fb313e06b5f980d3e4289384b086a68"
J Lab Clin Med. 1967 Jul;70(1):158-69.
Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase.
"www.ncbi.nlm.nih.gov/pubmed/6066618"
Paglia DE, Valentine WN.
PMID: 6066618
Title : [43] Malondialdehyde determination as index of lipid Peroxidation
Authors : H.H. Draper, M. Hadley
Book Chapter : Oxygen Radicals in Biological Systems Part B: Oxygen Radicals and Antioxidants
Publication Date : 1990
Direct Link : "www.sciencedirect.com/science/article/pii/007668799086135I"
Summary :
This chapter describes the malondialdehyde (MDA) as index of lipid peroxidation. The determination of malondialdehyde (MDA) has attracted widespread interest, because it appears to offer a facile means of assessing lipid peroxidation in biological materials. Malondialdehyde occurs in biological materials in free state and in various covalently bound forms. Urine also contains small amounts of MDA adducts with guanine, the phospholipid bases serine and ethanolamine, and other unidentified reactants. Free MDA is a minor and variable excretory product. It is apparent from the occurrence of these derivatives in urine that MDA forms adducts with proteins, nucleic acids, and other substances in vivo, and this compromises the assessment of lipid peroxidation in the tissues based on the determination of free MDA. The pH required for maximum yield of MDA varies among biological materials depending on the nature of the derivatives present. MDA may be generated during hydrolysis by the oxidation of polyunsaturated fatty acids (PUFA) in the sample and by the degradation of preexisting oxidation products. Pigments present in the sample, or generated during hydrolysis, also can interfere in the colorimetric assessment of MDA. These problems, and possibilities for their resolution, are discussed in the chapter.
PostgraduateForum Is a trading name of FindAUniversity Ltd
FindAUniversity Ltd, 77 Sidney St, Sheffield, S1 4RG, UK. Tel +44 (0) 114 268 4940 Fax: +44 (0) 114 268 5766
An active and supportive community.
Support and advice from your peers.
Your postgraduate questions answered.
Use your experience to help others.
Enter your email address below to get started with your forum account
Enter your username below to login to your account
An email has been sent to your email account along with instructions on how to reset your password. If you do not recieve your email, or have any futher problems accessing your account, then please contact our customer support.
or continue as guest
To ensure all features on our website work properly, your computer, tablet or mobile needs to accept cookies. Our cookies don’t store your personal information, but provide us with anonymous information about use of the website and help us recognise you so we can offer you services more relevant to you. For more information please read our privacy policy
Agree Agree