Use of Rat IgG

D

Could anyone explain why do we use rat IgG as a control rather than PBS injections in mice.

Avatar for sneaks

this has only resulted in me thinking of sugar mice mmm

P

Unfortunately I am reminded of the great plague.....

J

to determine nonspecific binding of rat
monoclonal antibodies to mouse cell surface antigens e.g. in FACS etc.. ....?

C

What an odd question.. were you asked this at interview or something?! :P Hehe!

Sounds to me like a method of showing non-specific binding or agglutination, as someone else has said....

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