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Advice wanted - Feeling hopeless in PhD and wanting to quit
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You can submit the chapters as method development chapters. You can write up every experiment you did, talk about the theory behind it and what you observed, then say that it's not good enough to use as a method and explain why.

It's not your fault that these methods didn't work and that's just part of the process when you're doing novel experiments. Talk to your personal tutor and supervisor about how you feel, they can advise you further.