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I am a post doc of biomedical science, worrying about the future career path
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I would like to join too.
I have finished my first draft of the thesis excluding one chapter and then just got so unmotivated. It feels like I am stuck and I cannot finish my thesis although it is just one chapter left. Please everybody else share how is it going for you and if you have been committed to this idea.

September 2013 Finish - Hopefully!
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Me too, because the funding runs out for me too!

unsupportive supervisors...
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I am in the third year of my PhD. My supervisor has never been any kind to me either, at first I thought if I published or got some results, things get better, I recently got a paper accepted in IEEE Journal and nothing changed, he is still the unsupported, bullying kind he was before. To add up to that I never received any kind of supervision or scientific help from him and honestly, this is whats killing me. He always pressures me about why I am not publishing or getting results but he never gives me any tip on how to get there. I, too, think about leaving my phd and working in coffee shop all the time. What I am trying to say is some people are just impossible to work with, they make the student feel insecure and stress all the time. I have worked with other supervisors (e.g. the one which I just published with) and I know this is not a general case, just an unlucky one. I cannot say what is best for you but to be honest I received more help from a stranger with one email than I did from him in all this time. What I can recommend for you, if I may, is to seek help elsewhere. Just do your best to find a way to not let him get you down and look for other researchers. Try researchgate.net, where you can ask stupid questions in your field.

3rd year stuck in a rut. No results!
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I am in the same place as you are and I get what you are saying. The only thing is you are luckier than me since your supervisors are happy with you. Mine keep reminding me (bullying me) how I am not a good scientist, hard worker, ect. Thanks for sharing your stories. I wish others do the same so it make us feel less of alone and losers.
I honestly think there is no advice anyone can give us because they are not in our shoes and the just don't understand the stress that we go through. I tried exercise, vacations and nothing works when you keep getting back to the same place you were before.